2,6,6-三甲基环己-1,3-二烯-1-甲腈合成路线 （共 15 条）
反应条件
1: 99 percent / NaBH4, CeCl3*7H2O / methanol / 0.08 h
2: 75 percent / p-toluenesulphonic acid / toluene / 30 h / Heating
View Scheme
参考文献
Kutney, James P.; Gunning, Philip J.; Clewley, Robin G.; Somerville, John; Rettig, Steven J.
Canadian Journal of Chemistry, 1992 , vol. 70, # 7 p. 2094 - 2114
反应条件
1: KOH; ethanol / 4 h
2: nBu4NCN / 8 h / 75 °C
3: 45 percent / ozone, sodium bicarbonate / ethyl acetate / 8 h / 0 °C
4: 92 percent / NaBH4 / ethanol / 1.5 h / Ambient temperature
5: conc. HCl / CH2Cl2 / 31 h
6: AIBN, tri-n-butyltin hydride / toluene / 2 h / Heating
7: 93 percent / ozone / ethyl acetate / 0.5 h / -78 °C
8: SOCl2 / methanol / 2 h
9: 99 percent / NaBH4, CeCl3*7H2O / methanol / 0.08 h
10: 75 percent / p-toluenesulphonic acid / toluene / 30 h / Heating
View Scheme
参考文献
Kutney, James P.; Gunning, Philip J.; Clewley, Robin G.; Somerville, John; Rettig, Steven J.
Canadian Journal of Chemistry, 1992 , vol. 70, # 7 p. 2094 - 2114
反应条件
1: nBu4NCN / 8 h / 75 °C
2: 45 percent / ozone, sodium bicarbonate / ethyl acetate / 8 h / 0 °C
3: 92 percent / NaBH4 / ethanol / 1.5 h / Ambient temperature
4: conc. HCl / CH2Cl2 / 31 h
5: AIBN, tri-n-butyltin hydride / toluene / 2 h / Heating
6: 93 percent / ozone / ethyl acetate / 0.5 h / -78 °C
7: SOCl2 / methanol / 2 h
8: 99 percent / NaBH4, CeCl3*7H2O / methanol / 0.08 h
9: 75 percent / p-toluenesulphonic acid / toluene / 30 h / Heating
View Scheme
参考文献
Kutney, James P.; Gunning, Philip J.; Clewley, Robin G.; Somerville, John; Rettig, Steven J.
Canadian Journal of Chemistry, 1992 , vol. 70, # 7 p. 2094 - 2114
反应条件
1: Ac2O
2: (i) Br2, CHCl3, (UV-irradiation), (ii) PhNEt2
View Scheme
参考文献
Eugster,C.H. et al.
Helvetica Chimica Acta, 1963 , vol. 46, p. 543 - 571
参考文献
Wendt
Chemische Berichte, 1941 , vol. 74, p. 1242,1246
