反应条件
1: dimethylformamide / 2 h / 100 - 120 °C
2: 33 percent / 1 N NaOH / H2O / 0.5 h / 80 °C
3: thionyl chloride / benzene / 2 h / Heating
4: 2.) HCl / 1.) ether, methylene chloride, RT, 1 h
View Scheme
参考文献
Nair, M. G.; Saunders, Colleen; Chen, Shiang-Yuan; Kisliuk, Roy L.; Gaumont, Y.
Journal of Medicinal Chemistry, 1980 , vol. 23, # 1 p. 59 - 65
