N-Boc-L-苯丙氨醛合成路线 （共 60 条）
反应条件
lithium aluminium tetrahydride in diethyl ether T=-50°C; 0.333333 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 56, # 13 p. 4161 - 4167
反应条件
oxalyl dichloride; dimethyl sulfoxide; N-ethyl-N,N-diisopropylamine in dichloromethane T=-35 - 0°C; Oxidation; Swern oxidation;
参考文献
Journal of Organic Chemistry, , vol. 65, # 22 p. 7609 - 7611
反应条件
2,4,6-trichloro-1,3,5-triazine; dimethyl sulfoxide; triethylamine in tetrahydrofuran T=-30 - 20°C; 2.5 h;
参考文献
Journal of Organic Chemistry, , vol. 66, # 23 p. 7907 - 7909
反应条件
1: Et3N / tetrahydrofuran 2: 83 percent / LiAlH4 / diethyl ether / 0.33 h / Ambient temperature View Scheme
参考文献
Chemical Communications, , # 5 p. 641 - 642
反应条件
1: 3A sieves, HCl (gas) / 2.5 h / Heating 2: TEA / dimethylformamide / 0.5 h / 60 °C 3: 100 percent / DIBAL-H / toluene / 2 h / -78 °C View Scheme
参考文献
Synthetic Communications, , vol. 22, # 7 p. 979 - 985
反应条件
tri-tert-butoxyaluminum hydride in tetrahydrofuran T=0°C; 1 h; Yield given;
参考文献
Helvetica Chimica Acta, , vol. 77, # 1 p. 150 - 154
反应条件
1: NaHCO3 / sonification 2: DIBAL-H / CH2Cl2 / -78 °C View Scheme
参考文献
Synlett, , # 3 p. 435 - 439
反应条件
1: NaBH4; AcOH / methanol; dioxane 2: MnO2 / CHCl3 / 18 h / 20 °C View Scheme
参考文献
Synlett, , # 18 art. no. G24405ST, p. 2802 - 2804
反应条件
1: NaBH4 / H2O / 0 °C 2: 99 percent / pyridine-SO3; NEt3; DMSO / CH2Cl2 / -10 °C View Scheme
参考文献
Bioorganic and medicinal chemistry letters, , vol. 14, # 1 p. 275 - 278
反应条件
1: 2.) Bu4NF / 1.) THF 2: 19 percent / pyridine, 4-(dimethylamino)pyridine / 16 h / Ambient temperature 3: 13 percent / 1 M NaOH / ethanol / 0.25 h / Ambient temperature 4: 96 percent / acetonitrile / 20 h / Heating 5: NaBH4 / methanol / 1 h / -10 °C 6: HgCl2 / acetonitrile; H2O / 0.25 h 7: NaCNBH3, 1 M HCl, 3-Angstroem molecular sieves / methanol / 112 h / Ambient temperature View Scheme
参考文献
Parkes, Kevin E. B.; Bushnell, David J.; Crackett, Peter H.; Dunsdon, Stephen J.; Freeman, Andrew C.; et al.
Journal of Organic Chemistry, 1994 , vol. 59, # 13 p. 3656 - 3664
