N-Boc-L-苯丙氨醛合成路线 （共 60 条）
反应条件
anhydrous sodium hydrogen carbonate in tetrahydrofuran; water
参考文献
Kaneka Corporation
Patent: US5744630 A1, 1998 ;
反应条件
1: With 3 A molecular sieve; hydroxylamine hydrochloride; 1,8-diazabicyclo[5.4.0]undec-7-ene in dichloromethane T=20°C; 10 h; 2: in dichloromethane T=20°C; 5 h; Further stages.;
参考文献
Zhu, Jia-Liang; Lee, Fa-Yen; Wu, Jen-Dar; Kuo, Chun-Wei; Shia, Kak-Shan
Synlett, 2007 , # 8 p. 1317 - 1319
反应条件
in tetrahydrofuran T=-5°C; 0.5 h; Yield given. Yields of byproduct given;
参考文献
Journal of Organic Chemistry, , vol. 50, # 23 p. 4615 - 4625
反应条件
1: 8 percent / Zn / tetrahydrofuran / 0.75 h / Heating 2: 98 percent / NaOH / tetrahydrofuran / 2 h View Scheme
参考文献
Sakaitani, Masahiro; Ohfune, Yasufumi
Journal of the American Chemical Society, 1990 , vol. 112, # 3 p. 1150 - 1158
反应条件
1.1: H2O; ethyl acetate 1.2: 6.45 g / conc. HCl / dioxane / 8 h / Heating 2.1: 32.5 percent / TEA / tetrahydrofuran; H2O View Scheme
参考文献
Yuan; Munoz; Wong; Haeggstrom; Wetterholm; Samuelsson
Journal of Medicinal Chemistry, 1993 , vol. 36, # 2 p. 211 - 220
反应条件
sodium tetrahydroborate in methanol T=20°C; 0.25 h; Inert atmosphere;
参考文献
Holan, Martin; Jahn, Ullrich
Organic Letters, 2014 , vol. 16, # 1 p. 58 - 61
反应条件
SmI2 in tetrahydrofuran
参考文献
Abbott Laboratories
Patent: US5712417 A1, 1998 ;
反应条件
TiCl3(DME)2; copper; zinc in ethylene glycol dimethyl ether T=0°C; 1 h; Yield given;
参考文献
Kempf, Dale J.; Sowin, Thomas J.; Doherty, Elizabeth M.; Hannick, Steven M.; Codavoci, LynnMarie; et al.
Journal of Organic Chemistry, 1992 , vol. 57, # 21 p. 5692 - 5700
反应条件
in tetrahydrofuran T=-5°C; 0.5 h; Yield given. Yields of byproduct given;
参考文献
Journal of Organic Chemistry, , vol. 50, # 23 p. 4615 - 4625
反应条件
in tetrahydrofuran 15 h; Ambient temperature;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1041 - 1046
