2,4,5-三脱氧-4-[[(1,1-二甲基乙氧基)羰基]氨基]-5-苯基-L-苏-戊糖酸合成路线 （共 42 条）
反应条件
1: With water; sodium hydroxide in tetrahydrofuran T=20°C; 1 h; 2: With hydrogenchloride in tetrahydrofuran; water Cooling;
参考文献
Yoo, Dongwon; Song, Jeeyun; Kang, Moon Sung; Kang, Eun-Sil; Kim, Young Gyu
Tetrahedron Asymmetry, 2011 , vol. 22, # 16-17 p. 1700 - 1704
反应条件
platinum(IV) oxide; oxygen in 1,4-dioxane; water T=55°C; 30 h;
参考文献
Sakaitani, Masahiro; Ohfune, Yasufumi
Tetrahedron Letters, 1987 , vol. 28, # 34 p. 3987 - 3990
反应条件
sodium hydroxide in tetrahydrofuran 2 h;
参考文献
Camplo; Niddam; Barthelemy; Faury; Mourier; Simon; Charvet; Trabaud; Graciet; Chermann; Kraus
European Journal of Medicinal Chemistry, 1995 , vol. 30, # 10 p. 789 - 800
反应条件
sodium hydroxide in 1,4-dioxane
参考文献
Vidyasagar Reddy; Venkat Rao; Iyengar
Tetrahedron Letters, 1999 , vol. 40, # 4 p. 775 - 776
反应条件
1: With bis(cyclohexanyl)borane in tetrahydrofuran T=20°C; 2: With dihydrogen peroxide; sodium hydrogencarbonate T=20°C;
参考文献
Alemany, Carme; Bach, Jordi; Garcia, Jordi; Lopez, Marta; Rodriguez, Ana B.
Tetrahedron, 2000 , vol. 56, # 47 p. 9305 - 9312
反应条件
1: 100 percent / Et3N / CH2Cl2 / 24 h / Ambient temperature 2: 96 percent / diisobutylaluminium hydride / hexane; CH2Cl2 / 0.1 h / -78 °C 3: 8 percent / Zn / tetrahydrofuran / 0.75 h / Heating 4: 98 percent / NaOH / tetrahydrofuran / 2 h View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 30, # 10 p. 789 - 800
反应条件
1: 8 percent / Zn / tetrahydrofuran / 0.75 h / Heating 2: 98 percent / NaOH / tetrahydrofuran / 2 h View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 30, # 10 p. 789 - 800
反应条件
1: Ba(OH)2 / ethanol; H2O / 30 h / 80 °C 2: triethylamine / tetrahydrofuran / 20 h / Ambient temperature 3: 55 percent / O2 / PtO2 / dioxane; H2O / 30 h / 55 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 28, # 34 p. 3987 - 3990
反应条件
1: N-chlorosuccinimide, Ph3P 2: 2,6-lutidine 3: AgF, (C5H5)3P, allylpalladium chloride dimer / acetonitrile / 3 h / Ambient temperature 4: 1.) 9-borabicyclo<3.3.1>nonane 2.) 30percent H2O2, 6N NaOH / 1.) THF, RT, 20 h 2.) ethanol, RT, 30 min 5: Ba(OH)2 / ethanol; H2O / 30 h / 80 °C 6: triethylamine / tetrahydrofuran / 20 h / Ambient temperature 7: 55 percent / O2 / PtO2 / dioxane; H2O / 30 h / 55 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 28, # 34 p. 3987 - 3990
反应条件
1: 2,6-lutidine 2: AgF, (C5H5)3P, allylpalladium chloride dimer / acetonitrile / 3 h / Ambient temperature 3: 1.) 9-borabicyclo<3.3.1>nonane 2.) 30percent H2O2, 6N NaOH / 1.) THF, RT, 20 h 2.) ethanol, RT, 30 min 4: Ba(OH)2 / ethanol; H2O / 30 h / 80 °C 5: triethylamine / tetrahydrofuran / 20 h / Ambient temperature 6: 55 percent / O2 / PtO2 / dioxane; H2O / 30 h / 55 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 28, # 34 p. 3987 - 3990
