2,4,5-三脱氧-4-[[(1,1-二甲基乙氧基)羰基]氨基]-5-苯基-L-苏-戊糖酸合成路线 （共 42 条）
反应条件
1: H2 / 5percent Rh-Al2O3 / ethanol / 16 h / 3040 - 3800 Torr 2: 96 percent / DEPC, triethylamine / tetrahydrofuran / 6 h / 0 °C 3: 4N HCl / dioxane / 0.5 h / Ambient temperature 4: 91 percent / DEPC, triethylamine / tetrahydrofuran / 6 h / 0 °C 5: 4N HCl / dioxane / 0.5 h / Ambient temperature 6: 71 percent / DEPC, triethylamine / tetrahydrofuran / 8 h / 0 °C View Scheme
参考文献
Nishi; Saito; Nagahori; Kataoka; Morisawa; Yabe; Sakurai; Higashida; Shoji; Matsushita; Iijima; Ohizumi; Koike
Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 1 p. 103 - 109
反应条件
hydrogenchloride in 1,4-dioxane
0.5 h; Ambient temperature;
参考文献
Rich; Sun; Ulm
Journal of Medicinal Chemistry, 1980 , vol. 23, # 1 p. 27 - 33
