(3S,4s)-4-氨基-3-羟基-5-苯基戊酸合成路线 （共 26 条）
反应条件
1: 67 percent / AcOH / toluene / Heating
2: 73 percent / cc. HCl / 80 °C
View Scheme
参考文献
Kondekar, Nagendra B.; Kandula, Subba Rao V.; Kumar, Pradeep
Tetrahedron Letters, 2004 , vol. 45, # 28 p. 5477 - 5479
反应条件
1: tetrahydrofuran
2: NaOH, H2O2 / H2O
3: Na, NH3
View Scheme
参考文献
Kawabata; Kiryu; Sugiura; Fuji
Tetrahedron Letters, 1993 , vol. 34, # 32 p. 5127 - 5130
反应条件
1: 85 percent / n-Bu3SnH / toluene / Heating
2: alkaline hydrolysis
View Scheme
参考文献
Misiti; Zappia
Tetrahedron Letters, 1990 , vol. 31, # 50 p. 7359 - 7362
反应条件
1: I2 / acetonitrile / Ambient temperature
2: 85 percent / n-Bu3SnH / toluene / Heating
3: alkaline hydrolysis
View Scheme
参考文献
Misiti; Zappia
Tetrahedron Letters, 1990 , vol. 31, # 50 p. 7359 - 7362
反应条件
hydrogenchloride; trifluoroacetic acid
1) 20 deg C, 1.5 h; 2) 80 deg C, 3 h; Yield given. Multistep reaction;
参考文献
Kanazawa, Alice; Gillet, Sandra; Delair, Philippe; Greene, Andrew E.
Journal of Organic Chemistry, 1998 , vol. 63, # 14 p. 4660 - 4663
反应条件
alkaline hydrolysis; Yield given;
参考文献
Misiti; Zappia
Tetrahedron Letters, 1990 , vol. 31, # 50 p. 7359 - 7362
