2-溴-2-(3,4-二氯苯基)乙酸合成路线 （共 3 条）
反应条件
N-bromosuccinmide; 2,2'-azo-bisisobutyronitrile in tetrachloromethane
T=35°C; 15 h; Irradiation;
参考文献
Anderson, Wayne K.; Milowsky, Arnold S.
Journal of Medicinal Chemistry, 1986 , vol. 29, # 11 p. 2241 - 2249
反应条件
1: 100 percent / aq. H2SO4 / 20 h / Heating
2: N-bromosuccinimide (NBS), 2,2'-azobis(2-methylpropanenitrile) / CCl4 / 15 h / 35 °C / Irradiation
View Scheme
参考文献
Anderson, Wayne K.; Milowsky, Arnold S.
Journal of Medicinal Chemistry, 1986 , vol. 29, # 11 p. 2241 - 2249
参考文献
Eli Lilly and Company
Patent: US6358971 B1, 2002 ;
