1: aq. NaCl, Tris buffer / 1-acyl-sn-glycerol-3-phosphate acyltransferase 2: H2O / phosphatidate phosphatase 3: cytidinediphosphocholine phosphocholinetransferase View Scheme

trifluoroacetic acid in dichloromethane 0.166667 h;

hydrogenchloride in 1,4-dioxane; water

1: 92 percent / pyridinium p-toluenesulfonate / CHCl3 / 1 h / 20 °C 2: 62 percent / NaBH4 / 1,2-dimethoxy-ethane / 1 h / 20 °C 3: 58 percent / tetrazole / acetonitrile; CHCl3 / 48 h / 20 °C 4: 90 percent / aq. H2O2 / CH2Cl2 5: 70 percent / DBU / toluene / 16 h / 110 °C 6: 86 percent / HCl / dioxane; H2O View Scheme

trimethylsilyl bromide in dichloromethane T=0 - 20°C; 4.16667 h; Inert atmosphere;

1: 58 percent / tetrazole / acetonitrile; CHCl3 / 48 h / 20 °C 2: 90 percent / aq. H2O2 / CH2Cl2 3: 70 percent / DBU / toluene / 16 h / 110 °C 4: 86 percent / HCl / dioxane; H2O View Scheme

1: 62 percent / NaBH4 / 1,2-dimethoxy-ethane / 1 h / 20 °C 2: 58 percent / tetrazole / acetonitrile; CHCl3 / 48 h / 20 °C 3: 90 percent / aq. H2O2 / CH2Cl2 4: 70 percent / DBU / toluene / 16 h / 110 °C 5: 86 percent / HCl / dioxane; H2O View Scheme