1: 87 percent / 1 h / Heating 2: 91 percent / H2 / Pd/C / ethanol / 1 h / 60 °C / 3750.3 Torr 3: 63 percent / NaHCO3 / dimethylformamide / 20 h / 90 °C 4: 1) Mg / 1) Et2O, toluene, 2) toluene, 2 h, reflux 5: KOH / bis-(2-hydroxy-ethyl) ether / 1.5 h / 210 °C View Scheme

1: 87 percent / 1 h / Heating 2: 91 percent / H2 / Pd/C / ethanol / 1 h / 60 °C / 3750.3 Torr 3: 63 percent / NaHCO3 / dimethylformamide / 20 h / 90 °C 4: 1) Mg / 1) Et2O, toluene, 2) toluene, reflux 5: KOH / bis-(2-hydroxy-ethyl) ether / 1.5 h / 210 °C View Scheme