2,4-二羟基-8-甲氧基喹啉合成路线 （共 10 条）
反应条件
PPA T=140 - 150°C; 0.666667 h;
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 22, # 12 p. 1254 - 1256
参考文献
Phytochemistry (Elsevier), , vol. 29, # 4 p. 1303 - 1306
反应条件
PPA 6 h; 120-140 deg C;
参考文献
Tetrahedron, , vol. 45, # 3 p. 757 - 762
反应条件
1: 95.5 percent 2: 80 percent / polyphosphoric acid / 6 h / 120-140 deg C View Scheme
参考文献
Tetrahedron, , vol. 45, # 3 p. 757 - 762
反应条件
1: 12 g / 1 N NaOH / 1 h / Ambient temperature 2: 87 percent / PPA / 0.67 h / 140 - 150 °C View Scheme
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 22, # 12 p. 1254 - 1256
反应条件
1: 2: With sodium carbonate 3:
参考文献
European Journal of Medicinal Chemistry, , vol. 45, # 10 p. 4467 - 4472
反应条件
hydrazine hydrate in 2-ethoxy-ethanol
36 h; Heating;
参考文献
Mulwad; Lohar
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2003 , vol. 42, # 8 p. 1937 - 1942
反应条件
1: 78 percent / hydrazine hydrate / 2-ethoxy-ethanol / 36 h / Heating
2: 65 percent / acetic acid / 16 h / 20 °C
View Scheme
参考文献
Mulwad; Lohar
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2003 , vol. 42, # 8 p. 1937 - 1942
反应条件
1: 87.7 percent / 30percent H2O2, conc.HCl / acetic acid / 0.5 h / 85 °C
2: 80.5 percent / methanol / 0.17 h / Heating
3: 56.8 percent / Zn, 1) AcOH, 2) HCl / methanol / Heating; 1) 10 min, 2) 5 min
4: KOH / dimethylformamide / 20 h / 60 - 65 °C
View Scheme
参考文献
Bhide, K. S.; Mujumdar, R. B.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983 , vol. 22, # 12 p. 1254 - 1256
反应条件
sodium hydroxide
0.75 h; Heating;
参考文献
Campbell, William E.; Davidowitz, Bette; Jackson, Graham E.
Phytochemistry (Elsevier), 1990 , vol. 29, # 4 p. 1303 - 1306
