(2-氧代哌啶-1-基)乙酸合成路线 （共 7 条）
反应条件
hydrogen; palladium hydroxide on carbon in methanol T=20°C; 4 h; Inert atmosphere;
参考文献
US2011/306599 A1, ;
Page/Page column 38 ;
反应条件
sodium iodide in acetone 24 h; Heating;
参考文献
Hassner, Alfred; Fischer, Bilha
Journal of Organic Chemistry, 1992 , vol. 57, # 11 p. 3070 - 3075
反应条件
trifluoroacetic acid in dichloromethane deprotection; 4 h;
参考文献
Li, Xiaobing; Murray, William V.; Jolliffe, Linda; Pulito, Virginia
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 10 p. 1093 - 1096
反应条件
sodium hydride in toluene T=60°C; 6 h;
参考文献
Dalla Croce, Piero; La Rosa, Concetta
Heterocycles, 2001 , vol. 55, # 10 p. 1843 - 1857
反应条件
1.1: NaH / toluene / 1 h / 0 °C 1.2: 100 percent / 10 h / 20 °C 2.1: 92 percent / TFA / CH2Cl2 / 4 h View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 10, # 10 p. 1093 - 1096
反应条件
1: 30 percent / BF3*Et2O / 12 h / Ambient temperature 2: 98 percent / NaI / acetone / 24 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 57, # 11 p. 3070 - 3075
反应条件
sodium iodide in acetone
参考文献
Tetrahedron Letters, , vol. 31, # 49 p. 7213 - 7214
