2,6-dimethylpyridine; triphenylphosphine; silver carbonate; palladium dichloride in 1-methyl-pyrrolidin-2-one T=130°C; 16 h; Inert atmosphere;

1: 2-EtO2C-C6H4-OTf With potassium acetate; triphenylphosphine; 4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl-4',4',5',5'-tetramethyl-1,3,2-dioxaborolane; bis-triphenylphosphine-palladium(II) chloride in toluene 12 h; Heating; 2: 2-nitrophenyl trifluoromethanesulfonate With tetrakis(triphenylphosphine) palladium(0); sodium carbonate in toluene Suzuki coupling reaction; 24 h; Heating; Further stages.;

1.1: 100 percent / pyridine / CH2Cl2 / 0.5 h / 20 °C 2.1: AcOK; bis(pinacolato)diboron; PPh3 / PdCl2(PPh3)2 / toluene / 12 h / Heating 2.2: 80 percent / Pd(PPh3)4; aq. Na2CO3 / toluene / 24 h / Heating View Scheme

1.1: 99 percent / pyridine / CH2Cl2 / 0.5 h / 20 °C 2.1: AcOK; bis(pinacolato)diboron; PPh3 / PdCl2(PPh3)2 / toluene / 12 h / Heating 2.2: 80 percent / Pd(PPh3)4; aq. Na2CO3 / toluene / 24 h / Heating View Scheme