1-(2-萘甲酰基 )乙醇合成路线 （共 127 条）
反应条件
(5aS,10bR)-5a,10b-dihydro-2-(pentafluorophenyl)-4H,6H-indeno[2,1-b][1,2,4]triazolo[4,3-d][1,4]oxazinium tetrafluoroborate; 3-benzylriboflavin tetraacetate; triethylamine in toluene T=20°C; 4 h; Resolution of racemateAirMolecular sieve; optical yield given as percent eeenantioselective reaction;
参考文献
Iwahana, Soichiro; Iida, Hiroki; Yashima, Eiji
Chemistry - A European Journal, 2011 , vol. 17, # 29 p. 8009 - 8013
反应条件
1: 4-(N,N-dimethlyamino)pyridine / dichloromethane / 20 °C / |Inert atmosphere 2: lipase from candida antartica / aq. phosphate buffer / 48 h / 30 °C View Scheme
参考文献
Kataoka, Noriyuki; Okudomi, Masayuki; Chihara, Naoka; Matsumoto, Kazutsugu
Letters in Organic Chemistry, 2012 , vol. 9, # 9 p. 615 - 621
反应条件
1: 4-(N,N-dimethlyamino)pyridine / dichloromethane / 20 °C / |Inert atmosphere 2: lipase from candida antartica / aq. phosphate buffer / 48 h / 30 °C View Scheme
参考文献
Kataoka, Noriyuki; Okudomi, Masayuki; Chihara, Naoka; Matsumoto, Kazutsugu
Letters in Organic Chemistry, 2012 , vol. 9, # 9 p. 615 - 621
反应条件
1: triethylamine; 4-(N,N-dimethlyamino)pyridine / diethyl ether 2: sodium carbonate / toluene / 72 h / 40 °C / |Schlenk technique; |Resolution of racemate; |Enzymatic reaction View Scheme
参考文献
Houiene, Zahia; Merabet-Khelassi, Mounia; Bouzemi, Nassima; Riant, Olivier; Aribi-Zouioueche, Louisa
Tetrahedron Asymmetry, 2013 , vol. 24, # 5-6 p. 290 - 296
反应条件
1: triethylamine; 4-(N,N-dimethlyamino)pyridine / diethyl ether 2: Candida antarctica lipase fraction B immobilized on acrylic resin / aq. phosphate buffer; diethyl ether / 48 h / 20 °C / pH 7 / |Resolution of racemate; |Enzymatic reaction View Scheme
参考文献
Houiene, Zahia; Merabet-Khelassi, Mounia; Bouzemi, Nassima; Riant, Olivier; Aribi-Zouioueche, Louisa
Tetrahedron Asymmetry, 2013 , vol. 24, # 5-6 p. 290 - 296
反应条件
1-methyl-1H-imidazole in tetrahydrofuran T=20°C; 2 h; Inert atmosphereAnhydrous conditions; Mechanism; Reagent/catalyst; enantioselective reaction;
参考文献
Leclercq, Loic; Suisse, Isabelle; Agbossou-Niedercorn, Francine
European Journal of Organic Chemistry, 2010 , # 14 p. 2696 - 2700
反应条件
1,3,5,7-tetrakis-(4-(diacetoxyiodo)phenyl)adamantane; 2,2,6,6-tetramethyl-1-piperidinyloxy, free radical in dichloromethane T=20°C;
参考文献
Green Chemistry, , vol. 14, # 5 p. 1493 - 1501
反应条件
palladium dichloro (η-2,5-norbornadiene); oxygen; (-)-sparteine in toluene T=80°C; 112 h;
参考文献
Journal of the American Chemical Society, , vol. 123, # 31 p. 7725 - 7726
反应条件
(1R)-N-oxyl-1-(N-benzylcarbamoyl)-8-azabicyclo[3.2.1]octane; sodium hydrogencarbonate; sodium bromide in dichloromethane; water T=0°C; Electrochemical reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Tetrahedron Asymmetry, , vol. 19, # 23 p. 2659 - 2665
反应条件
2,2,6,6-tetramethyl-1-piperidinyloxy, free radical; Candida antarctica B lipase; [RuCl2(p-cymene)]2; (E)-2-((1-hydroxy-2-methylpropan-2-ylimino)methyl)phenol in toluene T=70°C; 72 h; Inert atmosphereEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Tetrahedron Asymmetry, , vol. 22, # 18-19 p. 1790 - 1796
