2-(5-氯-2-硝基苯基)乙腈合成路线 （共 8 条）
反应条件
1.1: sodium hydride / N,N-dimethyl-formamide / 0.33 h 1.2: 80 °C 2.1: iron; acetic acid / water / 70 °C View Scheme
参考文献
Bujok, Robert; Wrobel, Zbigniew; Wojciechowski, Krzysztof; Trawczyski, Adam
Synlett, 2012 , vol. 23, # 18 p. 2682 - 2686,5
反应条件
sulfuric acid in water 0.333333 h; Heating;
参考文献
Loewe, Werner; Witzel, Sonja; Tappmeyer, Silvia; Albuschat, Rica
Journal of Heterocyclic Chemistry, 2004 , vol. 41, # 3 p. 317 - 326
反应条件
sodium hydroxide in ammonia
T=-50 - -30°C; 1 h;
参考文献
Makosza, Mieczyslaw; Winiarski, Jerzy
Journal of Organic Chemistry, 1984 , vol. 49, # 9 p. 1494 - 1499
反应条件
sodium hydride in dimethyl sulfoxide
T=20 - 25°C; 6.5 h;
参考文献
Jonczyk, Andrzej; Kowalkowska, Anna
Synthesis, 2002 , # 5 p. 674 - 680
反应条件
sodium hydroxide in dimethyl sulfoxide
1 h; Ambient temperature;
参考文献
Makosza, Mieczyslaw; Winiarski, Jerzy
Journal of Organic Chemistry, 1984 , vol. 49, # 9 p. 1494 - 1499
反应条件
sodium hydroxide; ammonia in diethyl ether
1 h; Ambient temperature;
参考文献
Makosza, Mieczyslaw; Winiarski, Jerzy
Journal of Organic Chemistry, 1984 , vol. 49, # 9 p. 1494 - 1499
参考文献
Takeuchi, Kumiko; Jirousek, Michael Robert; Paal, Michael; Ruhter, Gerd; Schotten, Theo
Patent: US2004/9976 A1, 2004 ;
Location in patent: Page/Page column 20 ;
反应条件
potassium tert-butylate; ammonia
T=-70°C; 6 h;
参考文献
Iwasaki, Genji; Hamana, Masatomo; Saeki, Seitaro
Heterocycles, 1982 , vol. 19, # 1 p. 162
