2-(2-氨基噻唑-5-基)乙酸甲酯氢溴酸合成路线 （共 2 条）
反应条件
in methanol
T=20 - 80°C; 102 h;
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2004/58752 A1, 2004 ;
Location in patent: Page 66 ;
WO 2004/058752 A1
反应条件
1: With sodium hydroxide; water in methanol
T=20°C; 3 h;
2: With hydrogenchloride in water
pH=3.5;
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2004/58752 A1, 2004 ;
Location in patent: Page 123-124 ;
WO 2004/058752 A1
