1: With sodium tris(acetoxy)borohydride; acetic acid in 1,2-dichloro-ethane T=20°C; 0.5 h; 2: With sodium hydrogencarbonate in water; 1,2-dichloro-ethane 3: With ammonium chloride; lithium hexamethyldisilazane more than 3 stages;

1: in tetrahydrofuran T=20°C; 1 h; 2: With lithium hexamethyldisilazane in tetrahydrofuran 16 h; 3: With hydrogenchloride in dichloromethane; water

triethylamine in dichloromethane; toluene

1,8-diazabicyclo[5.4.0]undec-7-ene in acetonitrile T=20°C; 15 h;

triethylamine in dichloromethane; toluene

palladium 10 on activated carbon; hydrogen in methanol T=20°C; P=760.051 Torr; 15 h;