5-(2-溴乙酰基)-2-(苯基甲氧基)苯甲酰胺合成路线 (共 4 条)
反应条件
bromine in chloroform
参考文献
Ashwell, Mark A; Solvibile Jr., William R; Han, Stella; Largis, Elwood; Mulvey, Ruth; Tillet, Jeffrey
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 24 p. 3123 - 3127
反应条件
1: 80 percent / NaOMe / methanol
2: 87 percent / Br2 / CHCl3
View Scheme
参考文献
Ashwell, Mark A; Solvibile Jr., William R; Han, Stella; Largis, Elwood; Mulvey, Ruth; Tillet, Jeffrey
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 24 p. 3123 - 3127
反应条件
1: 1.) NaOCH3 / 1.) DMF, 2.) DMF, heating, 7 h
2: Br2 / CHCl3 / 0.17 h / Heating
View Scheme
参考文献
Gold, Elijah H.; Chang, Wei; Cohen, Marvin; Baum, Thomas; Ehrreich, Steward; et al.
Journal of Medicinal Chemistry, 1982 , vol. 25, # 11 p. 1363 - 1370
反应条件
1: 80 percent / NaOMe / methanol
2: 87 percent / Br2 / CHCl3
View Scheme
参考文献
Ashwell, Mark A; Solvibile Jr., William R; Han, Stella; Largis, Elwood; Mulvey, Ruth; Tillet, Jeffrey
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 24 p. 3123 - 3127