反应条件
1.1: phosphorus tribromide / N,N-dimethyl-formamide 2.1: sodium hydroxide / tetrahydrofuran; water / 18 h / 20 °C 3.1: diphenyl phosphoryl azide; triethylamine / N,N-dimethyl-formamide / 1 h / 100 °C 4.1: trifluoroacetic acid / dichloromethane / 3 h / 20 °C 5.1: NOBF4 / tetrahydrofuran / 0.5 h / -10 °C 5.2: 0.03 h / 170 °C View Scheme
参考文献
Miles, Timothy J.; Axten, Jeffrey M.; Barfoot, Christopher; Brooks, Gerald; Brown, Pamela; Chen, Dongzhao; Dabbs, Steven; Davies, David T.; Downie, David L.; Eyrisch, Susanne; Gallagher, Timothy; Giordano, Ilaria; Gwynn, Michael N.; Hennessy, Alan; Hoover, Jennifer; Huang, Jianzhong; Jones, Graham; Markwell, Roger; Miller, William H.; Minthorn, Elizabeth A.; Rittenhouse, Stephen; Seefeld, Mark; Pearson, Neil
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 24 p. 7489 - 7495