反应条件
1: hydroxylamine hydrochloride, pyridine / 24 h / Heating
2: 1.) sodium hydride / 1.) DMF, benzene, 80 to 85 deg C, 3h, 2.) RT
3: 63 percent / 5percent aq. NaOH / ethanol / 0.5 h / Heating
View Scheme
参考文献
Shutske, Gregory M.; Setescak, Linda L.; Allen, Richard C.; Davis, Larry; Effland, Richard C.; et al.
Journal of Medicinal Chemistry, 1982 , vol. 25, # 1 p. 36 - 44
