(9-芴基)三苯基溴化磷合成路线 （共 10 条）
反应条件
1: aq. NH3 View Scheme
参考文献
Fletcher,T.L. et al.
J. Med. Chem., 1965 , vol. 8, p. 347 - 350
反应条件
18-crown-6 ether; potassium carbonate in dichloromethane Wittig reaction; 12 h; Heating;
参考文献
Ulmschneider, Sarah; Mueller-Vieira, Ursula; Klein, Christian D.; Antes, Iris; Lengauer, Thomas; Hartmann, Rolf W.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 5 p. 1563 - 1575
反应条件
1: aq. NH3 View Scheme
参考文献
Fletcher,T.L. et al.
J. Med. Chem., 1965 , vol. 8, p. 347 - 350
反应条件
in acetonitrile
Heating;
参考文献
Hintermann, Lukas; Ackerstaff, Jens; Boeck, Florian
Chemistry - A European Journal, 2013 , vol. 19, # 7 p. 2311 - 2321
反应条件
1: 9H-fluorene With N-bromosuccinmide; dibenzoyl peroxide in benzene
4 h; Reflux;
2: triphenylphosphine in benzene
48 h; Reflux;
参考文献
Wong, Michael Y.; Leung, Louis M.
Tetrahedron, 2010 , vol. 66, # 22 p. 3973 - 3977
反应条件
in benzene
12 h; Heating;
参考文献
Ulmschneider, Sarah; Mueller-Vieira, Ursula; Klein, Christian D.; Antes, Iris; Lengauer, Thomas; Hartmann, Rolf W.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 5 p. 1563 - 1575
参考文献
Wittig,G.; Schlosser,M.
Tetrahedron, 1962 , vol. 18, p. 1023 - 1028
反应条件
1: aq. NH3
View Scheme
参考文献
Fletcher,T.L. et al.
J. Med. Chem., 1965 , vol. 8, p. 347 - 350
反应条件
1: (9H-fluoren-9-yl)triphenylphosphonium bromide With potassium tert-butylate in tetrahydrofuran
0.5 h;
2: formaldehyd in tetrahydrofuran
T=30°C; Wittig reaction; 12 h;
参考文献
Wong, Michael Y.; Leung, Louis M.
Tetrahedron, 2010 , vol. 66, # 22 p. 3973 - 3977
参考文献
Hintermann, Lukas; Ackerstaff, Jens; Boeck, Florian
Chemistry - A European Journal, 2013 , vol. 19, # 7 p. 2311 - 2321
