1: N,N-dimethyl-1-(6-nitro-1H-indol-3-yl)methanamine With methyl iodide in tetrahydrofuran; water
0.166667 h; Reflux;
2: potassium cyanide in tetrahydrofuran; water
Reflux;
参考文献
Vertex Pharmaceuticals Incorporated
Patent: US2012/309758 A1, 2012 ;
Location in patent: Page/Page column 70 ;
US 20120309758 A1