2: H2, quinoline / Pd-BaSO4 / hexane 3: 98 percent / NaOAc / 0 °C View Scheme

magnesium 1.) THF, 40 - 50 deg C, 1 h, 2.) THF, 10 - 20 deg C, 1 h; Yield given. Multistep reaction;

Yield given. Multistep reaction;

1: 1.) Mg / 1.) THF, 40 - 50 deg C, 1 h, 2.) THF, 10 - 20 deg C, 1 h 2: Na, ethylene glycol / toluene / 98 - 101 °C 3: 77 percent / p-toluenesulfonic acid / pyridine / Heating View Scheme