2,5-二(3-甲基丁基)呋喃合成路线 （共 3 条）
反应条件
1: furan With n-butyllithium; N,N,N',N,-tetramethylethylenediamine in hexane
Cooling with iceReflux;
2: 1-bromo-3-methyl-butane in tetrahydrofuran; hexane
T=20°C; Cooling with ice;
参考文献
Kitamura, Chitoshi; Tsukuda, Hideki; Yoneda, Akio; Kawase, Takeshi; Kobayashi, Takashi; Naito, Hiroyoshi
European Journal of Organic Chemistry, 2010 , # 16 p. 3033 - 3040
反应条件
n-butyllithium
1) THF, hexane, 24h, RT, 2) 24h; Yield given. Multistep reaction;
参考文献
McKeown, Neil B.; Chambrier, Isabelle; Cook, Michael J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1990 , # 4 p. 1169 - 1177
反应条件
1: 1.) n-butyllithium / 1.) -30 deg C, 4 h., n-hexane, dry THF; 2.) r.temp.
2: 1.) n-butyllithium / 1.) -30 deg C, 4 h., n-hexane, dry THF; 2.) r.temp.
View Scheme
参考文献
Lissi, E. A.; Encinas, M. V.; Castaneda, F.; Olea, F. A.
Journal of Physical Chemistry, 1980 , vol. 84, # 3 p. 251 - 255
