5-(1H-吲哚-3-基甲基)-2,2-二甲基-1,3-二恶烷-4,6-二酮合成路线 (共 6 条)
反应条件
pyridinium p-toluenesulfonate in pyridine 84 h; Heating;
参考文献
Yu; Thrasher; McCowan; Mason; Mendelsohn
Journal of Medicinal Chemistry, 1991 , vol. 34, # 4 p. 1505 - 1508
反应条件
L-proline in acetonitrile
T=20°C; Condensation; 5 h;
参考文献
Rajeswaran; Labroo; Cohen; King
Journal of Organic Chemistry, 1999 , vol. 64, # 4 p. 1369 - 1371
反应条件
DL-proline in acetonitrile
T=85°C; 0.5 h; microwave irradiation;
参考文献
Nemes, Csaba; Laronze, Jean-Yves
Synthesis, 1999 , # 2 p. 254 - 257
反应条件
sodium tetrahydroborate in methanol
参考文献
Wright,A.D. et al.
Tetrahedron Letters, 1979 , p. 2325 - 2326
反应条件
1: 98 percent / H2O / 1 h / 25 °C
2: glacial AcOH / ethanol / 1 h
View Scheme
参考文献
Zia-Ebrahimi; Huffman
Synthesis, 1996 , # 2 p. 215 - 218
反应条件
acetic acid in ethanol
1 h;
参考文献
Zia-Ebrahimi; Huffman
Synthesis, 1996 , # 2 p. 215 - 218