(+)-乙基 (R)-3-羟基-3-苯丙酸盐合成路线 （共 53 条）
反应条件
1: cobalt(II) chloride / acetonitrile / 8 h / |Reflux 2: Saccharomyces cerrvisatae (ATCC 9080) / water / 48 h / 20 °C / |Enzymatic reaction View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 24, # 21-22 p. 1389 - 1394
反应条件
water; trifluoroacetic acid 1.) 0 deg C, 15 min; 2.) 0 deg C, 2 h; Yield given. Multistep reaction;
参考文献
Tetrahedron, , vol. 40, # 19 p. 3769 - 3776
反应条件
1: pyridine; 4-(N,N-dimethlyamino)pyridine / dichloromethane / 20 °C 2: Candida rugose type VII lipase; water / di-isopropyl ether / 15 h / 20 °C / Enzymatic reaction View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 22, # 16-17 p. 1672 - 1679
反应条件
ethanol Einleiten von Chlorwasserstoff;
参考文献
Journal of the Chemical Society, , p. 1663,1666, 1668
反应条件
2: ethanol / Einleiten von Chlorwasserstoff View Scheme
参考文献
Journal of the Chemical Society, , p. 1663,1666, 1668
反应条件
pig liver esterase in ethanol; water T=25°C; 20 h; further solvent and time; substitution effect, enzymatic hydrolysis, also with other esters; Product distribution;
参考文献
Gazzetta Chimica Italiana, , vol. 119, # 11 p. 581 - 584
反应条件
lipase PS-30 from Pseudomonas sp., phosphate buffer pH 7;
参考文献
Journal of Organic Chemistry, , vol. 57, # 15 p. 4289 - 4292
反应条件
samarium diiodide; sodium ethanolate 1.) THF, -78 deg C, 0.5 h; Multistep reaction. Title compound not separated from byproducts;
参考文献
Tetrahedron Letters, , vol. 39, # 38 p. 6899 - 6900
反应条件
lt;C7H2(CH3)2(C6H4)2C6H5gt;OTf; hydrogen fluoride multistep reaction; other reagent, reaction time; Product distribution;
参考文献
Journal of the American Chemical Society, , vol. 119, # 46 p. 11341 - 11342
参考文献
Journal of the Chemical Society, Chemical Communications, , # 23 p. 1460 - 1462
