(+)-乙基 (R)-3-羟基-3-苯丙酸盐合成路线 （共 53 条）
反应条件
Yield given. Multistep reaction;
参考文献
Journal of the Chemical Society, Chemical Communications, , # 23 p. 1460 - 1462
反应条件
immobilised Candida parapsilosis ATCC 7330 whole cells in ethanol; water T=25°C; 6 h;
参考文献
Padhi, Santosh Kumar; Titu; Pandian, N. Ganesh; Chadha, Anju
Tetrahedron, 2006 , vol. 62, # 21 p. 5133 - 5140
反应条件
1: immobilised Candida parapsilosis ATCC 7330 whole cells / H2O; ethanol / 25 °C 2: sodium borohydride View Scheme
参考文献
Padhi, Santosh Kumar; Titu; Pandian, N. Ganesh; Chadha, Anju
Tetrahedron, 2006 , vol. 62, # 21 p. 5133 - 5140
反应条件
1: immobilised Candida parapsilosis ATCC 7330 whole cells / H2O; ethanol / 25 °C 2: sodium borohydride View Scheme
参考文献
Padhi, Santosh Kumar; Titu; Pandian, N. Ganesh; Chadha, Anju
Tetrahedron, 2006 , vol. 62, # 21 p. 5133 - 5140
反应条件
1: immobilised Candida parapsilosis ATCC 7330 whole cells / H2O; ethanol / 25 °C 2: sodium borohydride 3: 48 percent / immobilised Candida parapsilosis ATCC 7330 whole cells / H2O; methanol / 6 h / 25 °C View Scheme
参考文献
Padhi, Santosh Kumar; Titu; Pandian, N. Ganesh; Chadha, Anju
Tetrahedron, 2006 , vol. 62, # 21 p. 5133 - 5140
反应条件
immobilised Candida parapsilosis ATCC 7330 whole cells in ethanol; water T=25°C;
参考文献
Padhi, Santosh Kumar; Titu; Pandian, N. Ganesh; Chadha, Anju
Tetrahedron, 2006 , vol. 62, # 21 p. 5133 - 5140
反应条件
sodium hydroxide in methanol Ambient temperature;
参考文献
Boaz, Neil W.
Journal of Organic Chemistry, 1992 , vol. 57, # 15 p. 4289 - 4292
反应条件
2: NaBrO; aq. NaOH solution View Scheme
参考文献
Lukes et al.
Chemistry and Industry (London, United Kingdom), 1958 , p. 527
反应条件
sodium hydroxide 1.) water, rt; 2.) ether, 0 deg C, 15 min; Multistep reaction;
参考文献
Bernardi, Anna; Colombo, Lino; Gennari, Cesare; Prati, Laura
Tetrahedron, 1984 , vol. 40, # 19 p. 3769 - 3776
反应条件
1.1: 94 percent / imidazole / CH2Cl2 / 20 °C 2.1: 82 percent / trimethylaluminum / toluene; CH2Cl2 / 20 °C 3.1: tert-butyllithium / toluene; pentane / 1.25 h / -78 - 0 °C 3.2: 72 percent / toluene; pentane / 2 h / -78 - 20 °C 4.1: 86 percent / p-toluenesulfonic acid / tetrahydrofuran; H2O / 12 h / 55 °C 5.1: 88 percent / triphenylphosphine; diethyl azodicarboxylate / tetrahydrofuran / 1 h / 0 °C View Scheme
参考文献
Hodgetts, Kevin J.
Tetrahedron Letters, 2001 , vol. 42, # 22 p. 3763 - 3766
