(5-乙酰基-2-乙酰氧基-苯基)乙酸酯合成路线 （共 16 条）
反应条件
1: CHCl3; bromine 2: dimethylformamide 3: acetic acid; aqueous HCl / beim anschliessenden Hydrieren an Palladium/Kohle View Scheme
参考文献
Howton et al.
Journal of the American Chemical Society, 1955 , vol. 77, p. 2896
反应条件
in di-isopropyl ether; butan-1-ol T=42 - 45°C; porcine pancreatic lipase (PPL);
参考文献
Parmar, V S; Khanduri, C H; Tyagi, O D; Prasad, A K; Gupta, Suman; et al.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1992 , vol. 31, # 12 p. 925 - 929
反应条件
sodium hydride in N,N-dimethyl-formamide
T=-78 - 20°C;
参考文献
Dangles, Olivier; Elhabiri, Mourad; Brouillard, Raymond
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1994 , # 12 p. 2587 - 2596
反应条件
sodium acetate
T=150°C;
参考文献
Neber; Burgard; Thier
Justus Liebigs Annalen der Chemie, 1936 , vol. 526, p. 277,287
反应条件
1.1: Pd(OPiv)2; [bis(acetoxy)iodo]benzene / α,α,α-trifluorotoluene / 120 °C / Inert atmosphere
1.2: 20 °C
2.1: pyridine
View Scheme
参考文献
Huang, Chunhui; Ghavtadze, Nugzar; Chattopadhyay, Buddhadeb; Gevorgyan, Vladimir
Journal of the American Chemical Society, 2011 , vol. 133, # 44 p. 17630 - 17633
反应条件
1.1: 1H-imidazole / tetrahydrofuran / 20 °C / Inert atmosphere
1.3: 20 °C
2.1: Pd(OPiv)2; [bis(acetoxy)iodo]benzene / α,α,α-trifluorotoluene / 120 °C / Inert atmosphere
2.2: 20 °C
3.1: pyridine
View Scheme
参考文献
Huang, Chunhui; Ghavtadze, Nugzar; Chattopadhyay, Buddhadeb; Gevorgyan, Vladimir
Journal of the American Chemical Society, 2011 , vol. 133, # 44 p. 17630 - 17633
反应条件
1: iron-powder; aq.-ethanolic sulfuric acid; NaI / Hydrogenation
2: sodium acetate / 100 °C
View Scheme
参考文献
Robinson; Leon
Anales de la Real Sociedad Espanola de Fisica y Quimica, 1931 , vol. 29, p. 415,419
Show Details
Leon; Robinson
Journal of the Chemical Society, 1931 , p. 2732,2733
Anales de la Real Sociedad Espanola de Fisica y Quimica, 1931 , vol. 29, p. 415,418
参考文献
Birnbaum; Powell
Journal of Organic Chemistry, 1939 , vol. 4, p. 139
反应条件
sodium iodide in acetonitrile
24 h; Ambient temperature; Product distribution;
参考文献
Corda, Luciana; Fadda, Anna Maria; Maccioni, Antonio; Maccioni, Anna Maria; Podda, Gianni
Journal of Heterocyclic Chemistry, 1988 , vol. 25, p. 311 - 314
反应条件
sodium iodide in acetonitrile
10 h; Ambient temperature; Product distribution;
参考文献
Corda, Luciana; Fadda, Anna Maria; Maccioni, Antonio; Maccioni, Anna Maria; Podda, Gianni
Journal of Heterocyclic Chemistry, 1988 , vol. 25, p. 311 - 314
