1: conc. H2SO4
2: H2 / 5percent Pd/C / ethanol / 45 °C
3: NaH / 1,2-dimethoxy-ethane / 20 h / Ambient temperature
4: sodium methoxide / methanol / 18 h / Heating
View Scheme
参考文献
Brown, Thomas H.; Blakemore, Robert C.; Blurton, Peter; Durant, Graham J.; Ganellin, C. Robin; et al.
European Journal of Medicinal Chemistry, 1989 , vol. 24, p. 65 - 72
1: H2 / 5percent Pd/C / ethanol / 45 °C
2: NaH / 1,2-dimethoxy-ethane / 20 h / Ambient temperature
3: sodium methoxide / methanol / 18 h / Heating
View Scheme
参考文献
Brown, Thomas H.; Blakemore, Robert C.; Blurton, Peter; Durant, Graham J.; Ganellin, C. Robin; et al.
European Journal of Medicinal Chemistry, 1989 , vol. 24, p. 65 - 72
1: NaH / 1,2-dimethoxy-ethane / 20 h / Ambient temperature
2: sodium methoxide / methanol / 18 h / Heating
View Scheme
参考文献
Brown, Thomas H.; Blakemore, Robert C.; Blurton, Peter; Durant, Graham J.; Ganellin, C. Robin; et al.
European Journal of Medicinal Chemistry, 1989 , vol. 24, p. 65 - 72