您好，欢迎来到魔法化学网！
合作交流
|
服务时间(9:30-18:00)
百科
百科
▼
百科
资讯
搜索
结构式
乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
首页
化合物百科
价格行情
资讯
化工导航
实验室工具
搜索
乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
吡曲克辛
合成路线
（共 12 条）
72676-85-8
→
反应条件
72732-56-0
吡曲克辛
反应条件
potassium hydroxide; hydrogen; palladium on activated charcoal in ethanol P=1810.02 - 2068.6 Torr; 36 h;
参考文献
Grivsky, Eugene M.; Lee, Shuliang; Sigel, Carl W.; Duch, David S.; Nichol, Charles A.
Journal of Medicinal Chemistry, 1980 , vol. 23, # 3 p. 327 - 329
93-02-7
2,5-二甲氧基苯甲醛
→
反应条件
72732-56-0
吡曲克辛
反应条件
1: 64 percent / piperidine / benzene; acetic acid / 3 h / Heating 2: 89 percent / H2 / 5percent Pd/C / ethyl acetate / 2 h / 1034.3 - 2068.6 Torr 3: 62 percent / diphenyl ether / 1.5 h / 195 - 230 °C 4: 40 percent / SOCl2*DMF / CHCl3 / 3 h / Heating 5: 38 percent / KOH, H2 / 5percent Pd/C / ethanol / 36 h / 1810.02 - 2068.6 Torr View Scheme
参考文献
Grivsky, Eugene M.; Lee, Shuliang; Sigel, Carl W.; Duch, David S.; Nichol, Charles A.
Journal of Medicinal Chemistry, 1980 , vol. 23, # 3 p. 327 - 329
72676-82-5
→
反应条件
72732-56-0
吡曲克辛
反应条件
1: 89 percent / H2 / 5percent Pd/C / ethyl acetate / 2 h / 1034.3 - 2068.6 Torr 2: 62 percent / diphenyl ether / 1.5 h / 195 - 230 °C 3: 40 percent / SOCl2*DMF / CHCl3 / 3 h / Heating 4: 38 percent / KOH, H2 / 5percent Pd/C / ethanol / 36 h / 1810.02 - 2068.6 Torr View Scheme
参考文献
Grivsky, Eugene M.; Lee, Shuliang; Sigel, Carl W.; Duch, David S.; Nichol, Charles A.
Journal of Medicinal Chemistry, 1980 , vol. 23, # 3 p. 327 - 329
72676-83-6
→
反应条件
72732-56-0
吡曲克辛
反应条件
1: 62 percent / diphenyl ether / 1.5 h / 195 - 230 °C 2: 40 percent / SOCl2*DMF / CHCl3 / 3 h / Heating 3: 38 percent / KOH, H2 / 5percent Pd/C / ethanol / 36 h / 1810.02 - 2068.6 Torr View Scheme
参考文献
Grivsky, Eugene M.; Lee, Shuliang; Sigel, Carl W.; Duch, David S.; Nichol, Charles A.
Journal of Medicinal Chemistry, 1980 , vol. 23, # 3 p. 327 - 329
72676-84-7
→
反应条件
72732-56-0
吡曲克辛
反应条件
1: 40 percent / SOCl2*DMF / CHCl3 / 3 h / Heating 2: 38 percent / KOH, H2 / 5percent Pd/C / ethanol / 36 h / 1810.02 - 2068.6 Torr View Scheme
参考文献
Grivsky, Eugene M.; Lee, Shuliang; Sigel, Carl W.; Duch, David S.; Nichol, Charles A.
Journal of Medicinal Chemistry, 1980 , vol. 23, # 3 p. 327 - 329
847234-66-6
→
反应条件
72732-56-0
吡曲克辛
反应条件
1: 43 percent / SbBr3; t-BuONO / various solvent(s) / 6 h / 4 - 10 °C 2: 38 percent / sodium methoxide; pyridine / 3 h / Heating View Scheme
参考文献
Chan, David C. M.; Rosowsky, Andre
Journal of Organic Chemistry, 2005 , vol. 70, # 4 p. 1364 - 1368
71493-76-0
2-氨基-3-氰基-4-甲基吡啶
→
反应条件
72732-56-0
吡曲克辛
反应条件
1: 92 percent / N-bromosuccinimide / dimethylformamide / 0 - 20 °C 2: 59 percent / PdCl2(dppf)*CH2Cl2 / tetrahydrofuran / 4 h / Heating 3: 43 percent / SbBr3; t-BuONO / various solvent(s) / 6 h / 4 - 10 °C 4: 38 percent / sodium methoxide; pyridine / 3 h / Heating View Scheme
参考文献
Chan, David C. M.; Rosowsky, Andre
Journal of Organic Chemistry, 2005 , vol. 70, # 4 p. 1364 - 1368
410547-37-4
→
反应条件
72732-56-0
吡曲克辛
反应条件
1: 33 percent / ammonia / methanol / 20 °C 2: 92 percent / N-bromosuccinimide / dimethylformamide / 0 - 20 °C 3: 59 percent / PdCl2(dppf)*CH2Cl2 / tetrahydrofuran / 4 h / Heating 4: 43 percent / SbBr3; t-BuONO / various solvent(s) / 6 h / 4 - 10 °C 5: 38 percent / sodium methoxide; pyridine / 3 h / Heating View Scheme
参考文献
Chan, David C. M.; Rosowsky, Andre
Journal of Organic Chemistry, 2005 , vol. 70, # 4 p. 1364 - 1368
180994-87-0
2-氨基-3-氰基-4-甲基-5-溴吡啶
→
反应条件
72732-56-0
吡曲克辛
反应条件
1: 59 percent / PdCl2(dppf)*CH2Cl2 / tetrahydrofuran / 4 h / Heating 2: 43 percent / SbBr3; t-BuONO / various solvent(s) / 6 h / 4 - 10 °C 3: 38 percent / sodium methoxide; pyridine / 3 h / Heating View Scheme
参考文献
Chan, David C. M.; Rosowsky, Andre
Journal of Organic Chemistry, 2005 , vol. 70, # 4 p. 1364 - 1368
153944-51-5
+
50-01-1
盐酸胍
→
反应条件
72732-56-0
吡曲克辛
反应条件
pyridine; sodium methylate 3 h; Heating;
参考文献
Chan, David C. M.; Rosowsky, Andre
Journal of Organic Chemistry, 2005 , vol. 70, # 4 p. 1364 - 1368
1
2
下一页
末页
到第
页
确定
