1-methyl-pyrrolidin-2-one; potassium carbonate; thiophenol Hydrolysis; 0.25 h; Heating;

potassium phosphate; Ni(PCy3)2Cl2; water; tri-cyclo-hexyl-phosphine in 1,4-dioxane T=110°C; 12 h; Inert atmosphere;

1: 1,1'-bis-(diphenylphosphino)ferrocene; [Ni0(1,5-cyclooctadiene)2]; N,N-dicyclohexylmethylamine / 1,4-dioxane / 20 h / 100 °C / Inert atmosphere 2: hydrogenchloride / 1,4-dioxane; water / 1 h / 20 °C / Inert atmosphere View Scheme

pyridine

in dimethyl sulfoxide T=55°C; kinetic isotope effect; Rate constant;

potassium phosphate; Ni(PCy3)2Cl2; water; tri-cyclo-hexyl-phosphine in 1,4-dioxane T=110°C; 12 h; Inert atmosphere;