反应条件
1: 39 percent / n-Bu3SnH, azobis(isobutyronitrile) (AIBN) / benzene / 1 h / Heating 2: 1.) p-toluenesulfinic acid, 2.) Et3N, 4-(N,N-dimethylamino)pyridine / 1.) CH3CN, H2O, RT, 48 h, 2.) CH2Cl2, 3 h 3: 1.) ozone, oxygen, 2.) dimethyl sulfide / 1.) CH2Cl2, 2.) 10 h 4: NaBH4 / methanol / 1 h / -40 °C 5: 93 percent / pyridine, 4-(N,N-dimethylamino)pyridine / 27 h 6: 50percent methanolic ammonia / 4 h 7: 67 percent / pyridine / 27 h 9: 97 percent / Lawesson's reagent / toluene / 1 h / Heating 10: 96 percent / W-2 Raney Ni / ethanol / 1 h / Heating 11: 63 percent / aq. MeNH2 / methanol / 46 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 53, # 26 p. 6022 - 6030
