6-溴-1,3-苯并二恶茂-4-甲醛合成路线 （共 3 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=85°C; 5 h; Inert atmosphereLarge scale; Reagent/catalyst;
参考文献
Jacks, Thomas E.; Belmont, Daniel T.; Briggs, Christopher A.; Horne, Nicole M.; Kanter, Gerald D.; Karrick, Greg L.; Krikke, James J.; McCabe, Richard J.; Mustakis, Jason G.; Nanninga, Thomas N.; Risedorph, Guy S.; Seamans, Ronald E.; Skeean, Richard; Winkle, Derick D.; Zennie, Thomas M.
Organic Process Research and Development, 2004 , vol. 8, # 2 p. 201 - 212
反应条件
1: bromine; potassium bromide; acetic acid / water / 2.42 h / 100 °C / |Inert atmosphere; |Large scale
2: acetic acid; water; hydrogen bromide / 39 h / 55 - 85 °C / 517.16 Torr / |Inert atmosphere; |Large scale
3: potassium carbonate / N,N-dimethyl-formamide / 5 h / 85 °C / |Inert atmosphere; |Large scale
View Scheme
参考文献
Jacks, Thomas E.; Belmont, Daniel T.; Briggs, Christopher A.; Horne, Nicole M.; Kanter, Gerald D.; Karrick, Greg L.; Krikke, James J.; McCabe, Richard J.; Mustakis, Jason G.; Nanninga, Thomas N.; Risedorph, Guy S.; Seamans, Ronald E.; Skeean, Richard; Winkle, Derick D.; Zennie, Thomas M.
Organic Process Research and Development, 2004 , vol. 8, # 2 p. 201 - 212
反应条件
1: acetic acid; water; hydrogen bromide / 39 h / 55 - 85 °C / 517.16 Torr / |Inert atmosphere; |Large scale
2: potassium carbonate / N,N-dimethyl-formamide / 5 h / 85 °C / |Inert atmosphere; |Large scale
View Scheme
参考文献
Jacks, Thomas E.; Belmont, Daniel T.; Briggs, Christopher A.; Horne, Nicole M.; Kanter, Gerald D.; Karrick, Greg L.; Krikke, James J.; McCabe, Richard J.; Mustakis, Jason G.; Nanninga, Thomas N.; Risedorph, Guy S.; Seamans, Ronald E.; Skeean, Richard; Winkle, Derick D.; Zennie, Thomas M.
Organic Process Research and Development, 2004 , vol. 8, # 2 p. 201 - 212
