2-氧代-2,3-二氢-1,3-苯并噁唑-6-羧酸甲酯合成路线 （共 6 条）
反应条件
in pyridine T=20°C; 36 h;
参考文献
METHYLGENE INC.
Patent: WO2007/118137 A1, 2007 ;
Location in patent: Page/Page column 106-107 ;
反应条件
triethylamine in dichloromethane T=20°C;
参考文献
RESVERLOGIX CORP.; JOHANSSON, Jan, O.; HANSEN, Henrik, C.; CHIACCHIA, Fabrizio, S.; WONG, Norman, C.W.
Patent: WO2007/16525 A2, 2007 ;
Location in patent: Page/Page column 89 ;
WO 2007/016525 A2
反应条件
1: hydrogenchloride / 48 h / 0 - 20 °C 2: tetrahydrofuran / 24 h / |Reflux View Scheme
反应条件
water in methanol T=48°C; pH 8.2 (phosphate or carbonate buffer); Rate constant;
参考文献
Journal of Organic Chemistry, , vol. 56, # 5 p. 1788 - 1800
反应条件
sodium hydroxide; toluene
参考文献
Journal fuer Praktische Chemie (Leipzig), , vol. <2> 92, p. 265
反应条件
1: With potassium hydroxide; water in tetrahydrofuran; methanol T=70 - 80°C; 120 h; Heating / reflux; 2: With hydrogenchloride in water
参考文献
RESVERLOGIX CORP.; JOHANSSON, Jan, O.; HANSEN, Henrik, C.; CHIACCHIA, Fabrizio, S.; WONG, Norman, C.W.
Patent: WO2007/16525 A2, 2007 ;
Location in patent: Page/Page column 89 ;
WO 2007/016525 A2
