3-(三氟甲基)二苯基甲醇合成路线 （共 14 条）
反应条件
1: With (R)-DTBM-Segphos; polymethylhydrosiloxane; copper(l) chloride; sodium t-butanolate in toluene T=0°C; 0.5 h; Inert atmosphere; 2: With sodium hydroxide; water in ethyl acetate; toluene 1 h; Inert atmosphere;
参考文献
Lee, Ching-Tien; Lipshutz, Bruce H.
Organic Letters, 2008 , vol. 10, # 19 p. 4187 - 4190
反应条件
[2,2']bipyridinyl; Fe/Cr/Ni in N,N-dimethyl-formamide Nozaki-Hiyama-Kishi reaction; Electrolysis;
参考文献
Durandetti; Nedelec; Perichon
Organic letters, 2001 , vol. 3, # 13 p. 2073 - 2076
反应条件
n-butyl-magnesium bromide in diethyl ether T=0°C; Yield given. Yields of byproduct given;
参考文献
Journal of Organic Chemistry, , vol. 56, # 7 p. 2573 - 2575
反应条件
NiBr2bipy in N,N-dimethyl-formamide Addition; reduction; Nozaki-Hiyama-Kishi reaction; Electrochemical reactionstainless steel (Fe/Cr/Ni = 72/18/10) anode;
参考文献
Durandetti, Muriel; Perichon, Jacques; Nedelec, Jean-Yves
Tetrahedron Letters, 1999 , vol. 40, # 51 p. 9009 - 9013
参考文献
Collection of Czechoslovak Chemical Communications, , vol. 38, p. 3496 - 3505
Journal of the American Chemical Society, , vol. 108, # 24 p. 7727 - 7738
反应条件
in diethyl ether T=0°C; Yield given. Yields of byproduct given;
参考文献
Journal of Organic Chemistry, , vol. 56, # 7 p. 2573 - 2575
反应条件
1: SOCl2 2: FeCl3 / 3 h / 20 - 40 °C 3: Zn, NaOH / aq. ethanol / 2 h / Heating View Scheme
参考文献
Bulletin de la Societe Chimique de France, , p. 587 - 593
反应条件
1: FeCl3 / 3 h / 20 - 40 °C 2: Zn, NaOH / aq. ethanol / 2 h / Heating View Scheme
参考文献
Bulletin de la Societe Chimique de France, , p. 587 - 593
反应条件
water in acetone T=25°C; var. solv.: MeOH, EtOH; Rate constantMechanism;
参考文献
Tetrahedron Letters, , vol. 36, # 38 p. 6919 - 6922
反应条件
in diethyl ether Reflux;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 20, # 4 p. 1378 - 1383
