4-(三氟甲基)二苯甲酮合成路线 （共 50 条）
反应条件
1.1: magnesium / tetrahydrofuran / 2 h / 20 - 85 °C 1.2: 0 - 20 °C / |Inert atmosphere 2.1: pyridinium chlorochromate; triethylamine / dichloromethane / 20 °C View Scheme
参考文献
Organic Letters, , vol. 14, # 18 p. 4850 - 4853,4
反应条件
1.1: magnesium / tetrahydrofuran / 2 h / 20 - 85 °C 1.2: 0 - 20 °C / |Inert atmosphere 2.1: pyridinium chlorochromate; triethylamine / dichloromethane / 20 °C View Scheme
参考文献
Organic Letters, , vol. 14, # 18 p. 4850 - 4853,4
反应条件
2: dichromate View Scheme
参考文献
Journal of the American Chemical Society, , vol. 108, # 24 p. 7727 - 7738
反应条件
1.1: potassium tert-butylate / isopropyl alcohol / Inert atmosphere 2.1: 1,1'-bis-(diphenylphosphino)ferrocene; 1,10-phenanthroline; Pd(F6-acac)2; cyclohexylamine; copper(I) bromide / quinoline / 10 h / 100 °C / Inert atmosphere; Molecular sieve 2.2: 1 h / 80 °C / Inert atmosphere View Scheme
参考文献
European Journal of Organic Chemistry, , # 32 p. 6486 - 6501
反应条件
palladium diacetate; caesium carbonate; triphenylphosphine in o-xylene T=150°C; 16 h; Inert atmosphere;
参考文献
Journal of Organic Chemistry, , vol. 78, # 4 p. 1665 - 1669
反应条件
1: diethyl ether 2: hypophosphorous acid; iodine / acetic acid / 60 °C 3: lithium perchlorate / acetonitrile; water / 5 h / 20 °C / |Electrolysis View Scheme
参考文献
Chemistry - A European Journal, , vol. 19, # 18 p. 5542 - 5545
反应条件
palladium diacetate; caesium carbonate; tri-cyclo-hexyl-phosphine in o-xylene 22 h; Heating; Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 68, # 13 p. 5236 - 5243
反应条件
1: bis(η3-allyl-μ-chloropalladium(II)); triethyl phosphite / 12 h / 100 °C 2: potassium phosphate; PdCl(NH2C6H4C6H4)(C6H4(CH3)4O3PC6H5); water / 2-methyl tetrahydrofuran / 44 h / 60 °C / Inert atmosphere View Scheme
参考文献
Journal of the American Chemical Society, , vol. 133, # 49 p. 19574 - 19577
反应条件
1: diethyl ether 2: hypophosphorous acid; iodine / acetic acid / 60 °C 3: lithium perchlorate / acetonitrile; water / 5 h / 20 °C / |Electrolysis View Scheme
参考文献
Chemistry - A European Journal, , vol. 19, # 18 p. 5542 - 5545
反应条件
potassium tert-butylate in tetrahydrofuran; tert-butyl alcohol T=35°C; Rate constantMechanism;
参考文献
Journal of Organic Chemistry, , vol. 47, # 25 p. 4841 - 4846
