formic acid; triethylamine; tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl-formamide T=110°C;

1: in ethanol Heating; 2: With hydrogenchloride in tetrahydrofuran T=20°C; 2 h;

1: phosphoryl chloride / 1,2-dichloro-ethane / r.t., 2 h, reflux, 3-4 h 2: 30 percent / H2 / catalytic hydrogenation View Scheme

1: 1.) sodium methylate / 1.) DMSO, 30 min, 75 deg C, 2.) 75 deg C, 5-10 min 2: 80 percent / propan-2-ol / 0.17 h / Heating 3: 35 percent / sodium methylate / ethanol / 40 h / Heating View Scheme