4-(3’-甲基苯基)氨基-3-吡啶磺酰胺合成路线 （共 5 条）
反应条件
1: in water T=90°C; 3 h; 2: With sodium hydrogencarbonate in water T=20°C; pH=7 - 8;
参考文献
TORCAN CHEMICAL LTD.
Patent: WO2004/89904 A2, 2004 ;
Location in patent: Page 7 ;
反应条件
in methanol T=39.85°C; 3 h;
参考文献
Hulita, Nada Kosutic; Danilovski, Aleksandar; Filic, Darko; Marinkovic, Marina; Mestrovic, Ernest; Dumic, Miljenko
Acta Crystallographica Section C: Crystal Structure Communications, 2005 , vol. 61, # 11 p. o648-o651
反应条件
1: With potassium carbonate in diethylene glycol dimethyl ether; water T=65 - 70°C; 0.583333 h; 2: With acetic acid in diethylene glycol dimethyl ether; water T=20 - 25°C; pH=5.3 - 5.7; 3 h;
参考文献
COSMA S.P.A.
Patent: US2004/138469 A1, 2004 ;
Location in patent: Page 4 ;
反应条件
1: With triethylamine in water; acetone 3 h; Heating / reflux; 2: With sodium hydroxide in water T=20 - 25°C; 3: With sulfuric acid in water; acetone T=50 - 55°C; 1 h; Product distribution / selectivity;
参考文献
FINETECH LABORATORIES LTD.
Patent: WO2003/97603 A1, 2003 ;
Location in patent: Page/Page column 46-47 ;
反应条件
pyridine
0.333333 h; Heating;
参考文献
Masereel, B.; Renard, P.; Schynts, M.; Pirotte, B.; Tullio, P. de; Delarge, J.
European Journal of Medicinal Chemistry, 1994 , vol. 29, # 7-8 p. 527 - 536
