4-氨基-5-氰基水杨酸乙酯合成路线 （共 3 条）
反应条件
1: ethyl acetoacetate With sodium in ethanol; water T=20°C; 0.5 h; 2: (ethoxymethylene)malononitrile in ethanol T=80°C; 0.5 h;
参考文献
NGUYEN, Duy; von Bonin, Arne; Haerter, Michael; Schirok, Hartmut; Mengel, Anne; Schaefer, Martina; von Ahsen, Oliver
Patent: US2009/186911 A1, 2009 ;
Location in patent: Page/Page column 18 ;
反应条件
1: malononitrile With sodium ethanolate in ethanol T=20°C; 0.333333 h; 2: ethyl ethoxymethyleneacetoacetate in ethanol 0.5 h; Heating;
参考文献
Kivrakidou, Olga; Braese, Stefan; Huelshorst, Frank; Griebenow, Nils
Organic Letters, 2004 , vol. 6, # 7 p. 1143 - 1146
反应条件
bromine in acetic acid
2 h; Ambient temperature;
参考文献
Schmidt; Dworczak
1986 , vol. 117, # 3 p. 393 - 406
