2-CHLORO-4-(TRIFLUOROMETHYL)THIAZOLE-5-CARBOXYLIC ACID合成路线 （共 4 条）
反应条件
sodium hydroxide in tetrahydrofuran 16 h; Ambient temperature;
参考文献
Lee, Len F.; Schleppnik, Francis M.; Howe, Robert K.
Journal of Heterocyclic Chemistry, 1985 , vol. 22, p. 1621 - 1630
反应条件
1: 92 percent / POCl3 / Heating 2: 73 percent / aq. NaOH / tetrahydrofuran / 16 h / Ambient temperature View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 22, p. 1621 - 1630
反应条件
1: 98 percent / SOCl2 / 6 h / Heating 2: 53 percent / 6 h / 130 - 140 °C View Scheme
参考文献
Lee, Len F.; Schleppnik, Francis M.; Howe, Robert K.
Journal of Heterocyclic Chemistry, 1985 , vol. 22, p. 1621 - 1630
反应条件
1: 98 percent / SOCl2 / 6 h / Heating
2: 95 percent / 6 h / Heating
View Scheme
参考文献
Lee, Len F.; Schleppnik, Francis M.; Howe, Robert K.
Journal of Heterocyclic Chemistry, 1985 , vol. 22, p. 1621 - 1630
