1-(2-甲基苯基)乙醇合成路线 （共 64 条）
反应条件
triethylamine; planar-chiral DMAP derivative in 1,1-dimethylpropan-1-ol T=0°C; Acetylation; 25.5 h;
参考文献
Journal of Organic Chemistry, , vol. 63, # 9 p. 2794 - 2795
反应条件
chiral 2-(3',5'-di-t-butylPh)-2-phosphabicyclo[3.3.0]octane in n-heptane T=-40°C; 14 h; Title compound not separated from byproducts;
参考文献
Journal of the American Chemical Society, , vol. 125, # 14 p. 4166 - 4173
反应条件
N-ethyl-N,N-diisopropylamine; CF3-PIP in chloroform T=0°C; 8.25 h; Resolution of racemate; Product distribution / selectivity;
参考文献
US2005/256150 A1, ;
Page/Page column 18 ;
反应条件
(R)-(+)-N-methylbenzoguanidine; trimethylacetic anhydride in diethyl ether T=20°C; 12 h; Resolution of racemate; optical yield given as percent ee;
参考文献
Nakata, Kenya; Shiina, Isamu
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 20 p. 7092 - 7096
反应条件
Escherichia coli BioH in hexane T=35°C; 28 h; Resolution of racemate; optical yield given as percent eeenantioselective reaction;
参考文献
Wang, Bo; Tang, Xiaoling; Liu, Ji; Yu, Hongwei
Tetrahedron Letters, 2010 , vol. 51, # 48 p. 6360 - 6364
反应条件
ChiroCLEC-PC in toluene 239.25 h;
参考文献
Journal of the American Chemical Society, , vol. 123, # 10 p. 2428 - 2429
反应条件
chiral substituted phosphabicyclo[3.3.0]octane*HBF4; triethylamine in 1,1-dimethylpropan-1-ol; dichloromethane T=-25°C; 20.2 h; Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 69, # 20 p. 6934 - 6937
反应条件
1: (S)-alpha-methylbenzyl alcohol With tert.-butyl lithium in diethyl ether; pentane T=-78 - 20°C; 4 h; 2: methyl iodide in diethyl ether; pentane T=-78 - 20°C; 19 h;
参考文献
Tetrahedron Asymmetry, , vol. 14, # 4 p. 439 - 447
反应条件
1: methylmagnesium bromide With titanium(IV) isopropylate; (Sa)-2'-[(R)-hydroxy(phenyl)methyl]-(1,1'-binaphthalen)-2-ol in toluene T=-40°C; 0.166667 h; Inert atmosphere; 2: 2-methyl-benzaldehyde in toluene T=-40°C; Grignard reaction; 4 h; Inert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
European Journal of Organic Chemistry, , # 34 p. 6851 - 6855
反应条件
(-)-DAIB in toluene T=40°C; Product distributionRate constant;
参考文献
Tetrahedron, , vol. 55, # 12 p. 3605 - 3614
