1-(2-甲基苯基)乙醇合成路线 （共 64 条）
反应条件
1.1: 59 percent / dimethylzinc; NaH / toluene; tetrahydrofuran / 22 h / 20 °C 2.1: t-BuLi / diethyl ether; pentane / 4 h / -78 - 20 °C 2.2: diethyl ether; pentane / 19 h / -78 - 20 °C View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 14, # 4 p. 439 - 447
反应条件
potassium fluoride; dihydrogen peroxide; potassium hydrogencarbonate in tetrahydrofuran; methanol 16 h; Inert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Organic and Biomolecular Chemistry, , vol. 7, # 21 p. 4470 - 4474
反应条件
methanol; sodium hydroxide T=20°C; Inert atmosphereHeating; optical yield given as percent ee;
参考文献
Journal of Organic Chemistry, , vol. 75, # 14 p. 4674 - 4685
反应条件
C39H31Cl2N4OPRu; potassium isopropoxide T=28°C; 0.5 h; Inert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Chemistry - A European Journal, , vol. 17, # 17 p. 4737 - 4741
反应条件
norephedrine mesitylsulphonamide; isopropyl alcohol 1.) ether, 30 min, -30 to -10 grad C, 2.) from -78 grad C to room temp., overnight; Further sulphonamide derivatives of norephedrine were investigated.; Product distribution;
参考文献
Tetrahedron Letters, , vol. 27, # 47 p. 5711 - 5714
反应条件
potassium peroxodisulfate
参考文献
Eisenlohr; Schulz
Chemische Berichte, 1924 , vol. 57, p. 1819
反应条件
C53H46ClN3P2Ru; potassium tert-butylate; acetone T=56°C; Oppenauer Oxidation; P=750.075 Torr; 0.0833333 h;
参考文献
Wang, Qingfu; Du, Wangming; Liu, Tingting; Chai, Huining; Yu, Zhengkun
Tetrahedron Letters, 2014 , vol. 55, # 9 p. 1585 - 1588
反应条件
(1R)-N-oxyl-1-(N-benzylcarbamoyl)-8-azabicyclo[3.2.1]octane; sodium hydrogencarbonate; sodium bromide in dichloromethane; water T=0°C; Electrochemical reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Demizu, Yosuke; Shiigi, Hirofumi; Mori, Hiroyuki; Matsumoto, Kazuya; Onomura, Osamu
Tetrahedron Asymmetry, 2008 , vol. 19, # 23 p. 2659 - 2665
反应条件
sodium hydrogencarbonate; sodium bromide; chiral azabicyclo-N-oxyl in dichloromethane T=0°C; Electrochemical reaction;
参考文献
Ebner, David C.; Trend, Raissa M.; Genet, Cedric; McGrath, Matthew J.; O'Brien, Peter; Stoltz, Brian M.
Angewandte Chemie - International Edition, 2008 , vol. 47, # 34 p. 6367 - 6370
反应条件
C50H42ClN2O3Ru in chloroform T=25°C; Molecular sieveResolution of racemate; Kinetics; enantioselective reaction;
参考文献
Mizoguchi, Hirotaka; Uchida, Tatsuya; Katsuki, Tsutomu
Angewandte Chemie - International Edition, 2014 , vol. 53, # 12 p. 3178 - 3182
Angew. Chem., 2014 , vol. 126, # 12 p. 3242 - 3246,5
