in N,N-dimethyl-formamide 4 h; Heating;

1: 40 percent / benzyltrimethylammonium chloride / CH2Cl2; H2O 2: 50 percent / KH / 2-methyl-propan-2-ol / 1.5 h / Ambient temperature 3: 68 percent / dimethylformamide / 4 h / Heating View Scheme

1: 50 percent / KH / 2-methyl-propan-2-ol / 1.5 h / Ambient temperature 2: 68 percent / dimethylformamide / 4 h / Heating View Scheme

sodium hydride; potassium carbonate 1.) DMF, RT, 0.5 h, 2.) DMF, a) overnight, b) reflux, 1.5 h; Multistep reaction;

sodium hydride; potassium carbonate 1.) DMF, RT, 0.5 h, 2.) DMF, a) overnight, b) reflux, 1.5 h; Multistep reaction;