反应条件
1.1: triethylamine; copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride / tetrahydrofuran / 3 h / 20 °C / |Inert atmosphere
2.1: tetrahydrofuran; acetic acid / 0.08 h / 20 °C / |Inert atmosphere
2.2: 4 h / 20 °C / |Inert atmosphere
3.1: hydroxylamine; potassium cyanide / tetrahydrofuran; methanol; water / 18 h / 20 °C
View Scheme
参考文献
Hale, Michael R.; Hill, Pamela; Lahiri, Sushmita; Miller, Matthew D.; Ross, Philip; Alm, Richard; Gao, Ning; Kutschke, Amy; Johnstone, Michele; Prince, Bryan; Thresher, Jason; Yang, Wei
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 8 p. 2362 - 2367
