4’-甲氧基[1,1’-联苯]-4-甲酸甲酯合成路线 （共 70 条）
反应条件
[Ni0(1,5-cyclooctadiene)2]; potassium phosphate; tri-cyclo-hexyl-phosphine in tetrahydrofuran T=20°C; Suzuki-Miyaura cross-coupling; 8 h; Inert atmosphere;
参考文献
Zhang, Na; Hoffman, David J.; Gutsche, Nicholas; Gupta, Jayesh; Percec, Virgil
Journal of Organic Chemistry, 2012 , vol. 77, # 14 p. 5956 - 5964
反应条件
anhydrous dipotassium phosphate; [1,3-bis(diphenylphosphino) propane] dichloronickel(II) in 1,4-dioxane T=100 - 110°C; Suzuki-Miyaura coupling reaction; Inert atmosphere;
参考文献
Gao, Han; Li, You; Zhou, Yi-Guo; Han, Fu-She; Lin, Ying-Jie
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 2-3 p. 309 - 314
反应条件
1: methyl 4-hydroxy-benzoate With potassium phosphate; triethylamine; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate in 1,4-dioxane T=100°C; 3 h; Inert atmosphere; 2: (4-methoxyphenyl)-boronic acid With [1,3-bis(diphenylphosphino) propane] dichloronickel(II) in 1,4-dioxane T=100 - 110°C; Suzuki-Miyaura coupling; Inert atmosphere;
参考文献
Chen, Guo-Jun; Huang, Jie; Gao, Lian-Xun; Han, Fu-She
Chemistry - A European Journal, 2011 , vol. 17, # 14 p. 4038 - 4042
反应条件
bis(1,5-cyclooctadiene)nickel (0); potassium phosphate; tri-cyclo-hexyl-phosphine in tetrahydrofuran T=25°C; 4 h; Inert atmosphere;
参考文献
Leowanawat, Pawaret; Zhang, Na; Safi, Mehtap; Hoffman, David J.; Fryberger, Miriam C.; George, Aiswaria; Percec, Virgil
Journal of Organic Chemistry, 2012 , vol. 77, # 6 p. 2885 - 2892
反应条件
1: 97 percent / Mg / tetrahydrofuran / 12 h / Ambient temperature 2: 64 percent / KF / Pd(OAc)2, P(o-Tol)3 / dimethylformamide / 120 °C View Scheme
参考文献
Tetrahedron, , vol. 50, # 28 p. 8301 - 8316
反应条件
1: C15H13O3Pol With trifluoroacetic acid in dichloromethane T=20°C; 0.833333 h; Wang resin; 2: diazomethane
参考文献
ACS Combinatorial Science, , vol. 16, # 5 p. 211 - 214
参考文献
Journal of the American Chemical Society, , vol. 66, p. 589,592
反应条件
1: CsF; Pd(OAc)2 / H2O / 22 h / 80 °C 2: ammonia / 20 °C View Scheme
参考文献
Organic Letters, , vol. 5, # 26 p. 5003 - 5005
反应条件
1.1: NaH / tetrahydrofuran / 20 °C 2.1: NiCl2(PPh3)2 / tetrahydrofuran / 0.25 h / 20 °C 2.2: 85 percent / tetrahydrofuran / 12 h / 20 °C View Scheme
参考文献
Journal of Organometallic Chemistry, , vol. 653, # 1-2 p. 91 - 97
参考文献
Organic Letters, , vol. 5, # 26 p. 5003 - 5005
