4’-甲氧基[1,1’-联苯]-4-甲酸甲酯合成路线 （共 70 条）
反应条件
1: KMnO4, aq. NaOH 2: (esterification) View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 33, p. 5 - 7
反应条件
NiCl2((PPh3)P)2; n-butyllithium 1.) THF, hexane, 0 deg C, 15 min, 2.) THF, hexane, 12 h, 20 deg C; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Tetrahedron Letters, , vol. 37, # 47 p. 8531 - 8534
反应条件
tetrakis(triphenylphosphine) palladium(0); sodium carbonate; potassium iodide 1.) DMF, 80 deg C; 2.) DME, reflux; 3.) MeOH, THF, reflux; Yield given. Multistep reaction;
参考文献
Tetrahedron Letters, , vol. 35, # 49 p. 9177 - 9180
反应条件
tetrakis(triphenylphosphine) palladium(0); sodium carbonate; potassium iodide 1.) DMF, 80 deg C; 2.) DME, reflux; 3.) MeOH, THF, reflux; Yield given. Multistep reaction;
参考文献
Tetrahedron Letters, , vol. 35, # 49 p. 9177 - 9180
反应条件
[Ni0(1,5-cyclooctadiene)2]; potassium phosphate; tri-cyclo-hexyl-phosphine in tetrahydrofuran T=20°C; Suzuki-Miyaura cross-coupling; Inert atmosphere; Kinetics;
参考文献
Journal of Organic Chemistry, , vol. 77, # 14 p. 5956 - 5964
参考文献
Journal of Organic Chemistry, , vol. 68, # 11 p. 4189 - 4194
参考文献
Bulletin of the Chemical Society of Japan, , vol. 33, p. 5 - 7
反应条件
hydrogenchloride Combinatorial reaction / High throughput screening (HTS); Product distribution / selectivity;
参考文献
US2007/43234 A1, ;
Page/Page column 51 ;
反应条件
lithium aluminium tetrahydride in tetrahydrofuran Heating;
参考文献
Matsumoto, Takahiro; Katayama, Nozomi; Mabuchi, Hiroshi
Patent: US2003/144338 A1, 2003 ;
反应条件
1: With sodium hydroxide; water in tetrahydrofuran T=20°C; 16.5 h; Heating / reflux; 2: With hydrogenchloride in tetrahydrofuran; water
参考文献
WYETH
Patent: WO2005/30702 A1, 2005 ;
Location in patent: Page/Page column 60 ;
