反应条件
1: 1.) sodium ethoxide / 1.) benzene, 2 h, 2.) DMF, 100 deg C, 20 h
2: 48percent HBr, glacial acetic acid / 120 h / Heating
3: H2SO4
4: 27.6 percent / NH3 / methanol / 168 h / Ambient temperature
5: 51 percent / NaBH4 / ethanol / 20 h / Ambient temperature
View Scheme
参考文献
Kundu
Journal of Medicinal Chemistry, 1980 , vol. 23, # 5 p. 512 - 516
