雌甾-1,3,5(10),6-四烯-3,17-二醇合成路线 （共 19 条）
反应条件
hydrogenchloride; methyllithium in tetrahydrofuran; water
参考文献
Lathe, Richard Frank; Seckl, Jonathan Robert; Martin, Keith Frank; Wulfert, Ernst Arne
Patent: US2003/92692 A1, 2003 ;
反应条件
methanol; sodium tetrahydroborate T=0 - 5°C; 2 h;
参考文献
Rao, Pemmaraju N.; Wang, Zhiqiang
Steroids, 1997 , vol. 62, # 6 p. 487 - 490
反应条件
potassium hydroxide in ethanol; dichloromethane 1 h; Ambient temperature;
参考文献
Ciattini, Pier Giuseppe; Morera, Enrico; Ortar, Giorgio
Synthetic Communications, 1990 , vol. 20, # 9 p. 1293 - 1297
反应条件
methyllithium in N,N-dimethyl-formamide 18.5 h; Ambient temperature;
参考文献
Gill, Julie C.; Marples, Brian A.; Traynor, John R.
Synthetic Communications, 1989 , vol. 19, # 1, 2 p. 155 - 158
3434-45-5[(8R,9S,13S,14S,17S)-3-乙酰氧基-13-甲基-6-氧代-8,9,11,12,14,15,16,17-八氢-7H-环戊二烯并[a]菲-17-基]乙酸酯
→
反应条件
1: ethanol / 4 h / Heating 2: 100 percent / ethanolic KOH 3: 70 percent / MeLi / dimethylformamide / 18.5 h / Ambient temperature View Scheme
参考文献
Synthetic Communications, , vol. 19, # 1, 2 p. 155 - 158
反应条件
1: 84 percent / Et3N, formic acid / palladium acetate-triphenylphosphine / dimethylformamide / 1.5 h / 60 °C 2: 100 percent / KOH / ethanol; CH2Cl2 / 1 h / Ambient temperature View Scheme
参考文献
Synthetic Communications, , vol. 20, # 9 p. 1293 - 1297
反应条件
lithium aluminium tetrahydride
参考文献
Journal of the American Chemical Society, , vol. 72, p. 4534,4539
反应条件
1: CCl4; N-bromo-succinimide 2: 2,4,6-trimethyl-pyridine 3: 600 °C 4: LiAlH4 View Scheme
参考文献
Journal of the American Chemical Society, , vol. 72, p. 4534,4539
反应条件
1: diethyl ether; acetic acid; bromine 2: 2,4,6-trimethyl-pyridine 3: 600 °C 4: LiAlH4 View Scheme
参考文献
Journal of the American Chemical Society, , vol. 72, p. 4534,4539
反应条件
1: 600 °C 2: LiAlH4 View Scheme
参考文献
Journal of the American Chemical Society, , vol. 72, p. 4534,4539
