1-[2-溴-1-[(2-甲基丙烷-2-基)氧基]乙基]-4-甲氧基苯合成路线 （共 8 条）
反应条件
1: K2CO3 / dimethylformamide / 2 h / 110 °C 2: 10percent aq. H2SO4 / Heating 3: 69 percent / TFA, 36 N H2SO4 / 3.5 h / 25 °C View Scheme
参考文献
Weinstock; Ladd; Wilson; Brush; Yim; Gallagher Jr.; McCarthy; Silvestri; Sarau; Flaim
Journal of Medicinal Chemistry, 1986 , vol. 29, # 11 p. 2315 - 2325
反应条件
1: K2CO3 / dimethylformamide / 2 h / 110 °C 2: 10percent aq. H2SO4 / Heating 3: 69 percent / TFA, 36 N H2SO4 / 3.5 h / 25 °C 4: 95 percent / BBr3 / CH2Cl2 / 3 h / 25 °C View Scheme
参考文献
Weinstock; Ladd; Wilson; Brush; Yim; Gallagher Jr.; McCarthy; Silvestri; Sarau; Flaim
Journal of Medicinal Chemistry, 1986 , vol. 29, # 11 p. 2315 - 2325
反应条件
1: K2CO3 / dimethylformamide / 2 h / 110 °C 2: 10percent aq. H2SO4 / Heating View Scheme
参考文献
Weinstock; Ladd; Wilson; Brush; Yim; Gallagher Jr.; McCarthy; Silvestri; Sarau; Flaim
Journal of Medicinal Chemistry, 1986 , vol. 29, # 11 p. 2315 - 2325
反应条件
N,N'-dibromo-N,N'-(1,2-ethanediyl)bis(p-toluenesulfonamide); ammonium acetate
T=20°C; 0.3 h;
参考文献
Kazemi, Foad; Kakroudi, Mazaher Abdollahi
Bulletin of the Korean Chemical Society, 2013 , vol. 34, # 2 p. 500 - 504
反应条件
magnesium oxide; magnesium sulfate
1.25 h; Heating;
参考文献
Weinstock; Ladd; Wilson; Brush; Yim; Gallagher Jr.; McCarthy; Silvestri; Sarau; Flaim
Journal of Medicinal Chemistry, 1986 , vol. 29, # 11 p. 2315 - 2325
反应条件
1: 86.4 percent / Br2 / CH2Cl2 / -5 - 0 °C
2: 95 percent / MgSO4, MgO / 1.25 h / Heating
View Scheme
参考文献
Weinstock; Ladd; Wilson; Brush; Yim; Gallagher Jr.; McCarthy; Silvestri; Sarau; Flaim
Journal of Medicinal Chemistry, 1986 , vol. 29, # 11 p. 2315 - 2325
反应条件
1: pyridine, 12 N aq. HCl, tert-butylhydroquinone / 1.5 h / 125 °C
2: 86.4 percent / Br2 / CH2Cl2 / -5 - 0 °C
3: 95 percent / MgSO4, MgO / 1.25 h / Heating
View Scheme
参考文献
Weinstock; Ladd; Wilson; Brush; Yim; Gallagher Jr.; McCarthy; Silvestri; Sarau; Flaim
Journal of Medicinal Chemistry, 1986 , vol. 29, # 11 p. 2315 - 2325
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=110°C; 2 h;
参考文献
Weinstock; Ladd; Wilson; Brush; Yim; Gallagher Jr.; McCarthy; Silvestri; Sarau; Flaim
Journal of Medicinal Chemistry, 1986 , vol. 29, # 11 p. 2315 - 2325
