氨基[4-(甲硫基)苯基]乙酸合成路线 (共 3 条)
反应条件
1: With zinc(II) iodide
T=20°C; 18 h;
2: With ammonia in methanol
T=45°C; 2 h;
3: With hydrogenchloride in water
T=110°C; 5 h;
参考文献
Chu, Xin-Jie; Fotouhi, Nader; Huby, Nicholas J.S.; Kong, Norman; McDermott, Lee Apostle; Moliterni, John; Zhang, Zhuming
Patent: US2006/41146 A1, 2006 ;
Location in patent: Page/Page column 31-32 ;
US 20060041146 A1
反应条件
hydrogenchloride
4 h; Heating;
参考文献
Barnish; Cross; Danilewicz; Dickinson; Stopher
Journal of Medicinal Chemistry, 1981 , vol. 24, # 4 p. 399 - 404
反应条件
1: 70 percent / conc. H2SO4 / acetic acid / Ambient temperature
2: 41 percent / aq. conc. HCl / 4 h / Heating
View Scheme
参考文献
Barnish; Cross; Danilewicz; Dickinson; Stopher
Journal of Medicinal Chemistry, 1981 , vol. 24, # 4 p. 399 - 404